Endemic Kaposi’s Disease Complicated by Osteolysis of the Fourth Metatarsal of the Left Foot: A Case Report at Kindu General Referral Hospital, Democratic Republic of Congo

¹Middle Lualaba University of Kalima (UML/Kalima), Democratic Republic of Congo

²Kindu General Referral Hospital, Democratic Republic of Congo

³Faculty of Medicine, University of Lubumbashi, Democratic Republic of Congo

⁴Higher Institute of Health Sciences / Maniema Red Cross (ISSS-CR/MMA), Democratic Republic of Congo

⁵Faculty of Medicine, Mapon University, Democratic Republic of Congo

^*Corresponding author: Aliamutu Kamango, Assistant at the Faculty of Medicine, Middle Lualaba University, Democratic Republic of Congo, Phone: +243 80 86 10 184, Email: [email protected]

Received Date: June 04, 2026

Published Date: September 25, 2026

Citation: Kamango A, et al. (2026). Endemic Kaposi’s Disease Complicated by Osteolysis of the Fourth Metatarsal of the Left Foot: A Case Report at Kindu General Referral Hospital, Democratic Republic of Congo. Mathews J Dermatol. 10(1):33.

Copyrights: Kamango A, et al. © (2026).

ABSTRACT

Kaposi’s disease (KD), formerly known as Kaposi’s sarcoma (KS), is a rare tumor first described by Moritz Kaposi in Vienna among Ashkenazi Jews. Since this original description, three other forms of Kaposi’s disease have been identified. This was a 37-year-old patient with no significant past medical history, who presented with a large, ulcerated, exophytic, and recurrent swelling on the dorsal surface of the left foot. The condition reportedly began five years earlier with the appearance of an erythematous macule, which gradually progressed into a slightly pigmented papule and then into a nodule. The diagnosis of endemic Kaposi’s disease, fibroblastic type, was established. After a multidisciplinary consultation meeting, surgical excision of the mass was planned, followed by adjuvant chemotherapy with Bleomycin according to the following protocol: a 15 IU vial of Bleomycin diluted in 40 mL of 0.9% saline, administered at a rate of 13 drops per minute every five days for eight weeks. The patient showed a favorable response to this treatment after one month. Endemic (African) Kaposi’s disease in its florid, vegetative form, characterized by large tumor lesions and osseous involvement, is rare.

Keywords: Disease, Endemic Kaposi’s Disease, Bone Lysis, Kindu