Mathews Journal of Case Reports


Previous Issues Volume 5, Issue 1 - 2020

Delayed Appearance of Klein-Levin Syndrome Caused by Traumatic Brain Injury: A Case Report

Ali Javadpour1, Shekoofeh Yaghmaei2*, Nejla Mostafeenezhad1, Nima Derakhshan3,  Peter Schofield4

1Department of psychiatry, Shiraz University of Medical Sciences, Shiraz, Iran

2Shiraz University of Medical Sciences, Shiraz, Iran

3Department of neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran

4The University of Newcastle, Australia
*Corresponding author: Shekoofeh Yaghmaei, Medical Doctor, Shiraz University of Medical Sciences, Namazi Hospital, Namazi Square, Shiraz, Iran, Postal Code: 71937–11351, Tel/Fax: +98–713–6474259; E-mail: [email protected]

Received Date: July 28, 2020
Publication Date: October 20, 2020
Copyright: Yaghmaei S, et al. ©2020
Citation: Javadpour A. (2020). Delayed appearance of Klein-Levin Syndrome caused by traumatic brain injury: A case report. Mathews J Case Rep. (5)1:63.



: The combination of hypersomnia and any of: hyper-phagia, hyper-sexuality, or mood changes is known as Klein-Levin Syndrome. This syndrome is quite infrequent and mostly restricted to adolescent males.

Case Description: A young patient with KLS is presented in this report. He was presented with relapsing-remitting hypersomnia and irritability more than two years after incurring a traumatic brain injury. Magnetic resonance imaging (MRI) showed hyperintensity in the posterolateral part of the right temporal region, matched with the brain injuries caused by the old trauma. His extremely long sleep episodes forced medical team to provide him with some necessary basic cares such as nasogastric tube and urinary catheter. Five consecutive weeks of taking modafinil got his sleep pattern back to normal.

Conclusion: In addition to medical treatment which is inevitable for severe cases, family and social support is extremely vital for managing KLS patients.

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