Information Links
Previous issues
Related Conferences
Previous Issues Volume 11, Issue 1 - 2026
Prebiotic Supplementation with Partially Hydrolyzed Guar Gum and Inulin Improves Bowel Habits and Gut Functional Markers: A Case Series Study
Vania Mattoso Ribeiro¹, Ana Beatriz Baptistella², Silvana Paiva Orlandi³, Katherine Guerra4, Nathalia Laganaro4, Valeria Abrahao Schilling Rosenfeld4,*
1Federal University Fluminense, Brazil
2Independent Researcher, Brazil
3Postgraduate Program in Nutrition and Foods, University Hospital/EBSERH, Federal University of Pelotas, Brazil
4Nestle Health Science, Brazil
*Corresponding Author: Valeria Abrahao Schilling Rosenfeld, Nestle Health Science, São Paulo, Brazil, ORCID: 0000-0003-2372-9649, Email: [email protected]
Received Date: March 13, 2026
Published Date: March 30, 2026
Citation: Ribeiro VM, et al. (2026). Prebiotic Supplementation with Partially Hydrolyzed Guar Gum and Inulin Improves Bowel Habits and Gut Functional Markers: A Case Series Study. Mathews J Gastroenterol Hepatol. 11(1):41.
Copyrights: Ribeiro VM, et al. © (2026).
ABSTRACT
Prebiotic fibers play a crucial role in regulating intestinal motility and contribute to improvements in gastrointestinal symptoms associated with altered transit and fermentative activity. The aim of this exploratory case series was to evaluate the effects of a fiber blend containing inulin and partially hydrolyzed guar gum on bowel habits, gastrointestinal symptoms, and biochemical markers in adults reporting constipation and/or diarrhea. Two women received supplementation for 36 days, including a 6-dayramp-up phase until reaching 22g/day. Clinical symptoms, stool characteristics, biochemical markers, and functional stool parameters were assessed at baseline and post-intervention. Both cases showed improvements in bowel frequency and/or stool consistency, with progression on the Bristol Stool Form Scale. Reductions were observed in fecal calprotectin, zonulin, and fecal fat, suggesting improved intestinal inflammatory status and digestive function. Systemic metabolic and hepatic biomarkers remained stable, reinforcing the safety of the intervention. These findings support the potential benefits of prebiotic fiber supplementation for bowel function and gut-related biomarkers, warranting further studies with larger samples.
Keywords: Gut Health, Constipation, Soluble Fiber, Prebiotic Fiber Supplementation.
