Mathews Journal of Gastroenterology & Hepatology

2572-6471

Previous Issues Volume 7, Issue 1 - 2022

Gastrointestinal Stromal Tumor (GIST) Cecal in Pediatrics? Clinical Case

César Abraham Ramírez-Franco1, Adrián Valle Partida2, Segundo Yépez-Vallejo3, Michelle Castro Barrios4, Davinia Suárez Flores5, Guillermo Padrón Arredondo6,*

1General Surgery Resident, General Surgery Service of Hospital General of Playa del Carmen, México

2Pediatric surgeon, General Surgery Service of Hospital General of Playa del Carmen, México

3,6General surgeons, General Surgery Service of Hospital General of Playa del Carmen, México

4,5Pathologists, General Surgery Service of Hospital General of Playa del Carmen, México

*Corresponding author: Guillermo Padrón-Arredondo, General Surgery Service of Hospital General of Playa del Carmen, Av. Constituyentes s/n with 35 Street, Col. Ejidal, Solidaridad Playa del Carmen, Q. Roo- PC: 77712, México, Tel: +52 984 876 2267, ORCID: 0000-0001-6049-5672; E-mail: [email protected].

Received Date: December 13, 2022

Published Date: December 31, 2022

Citation: Padrón-Arredondo G, et al. (2022). Gastrointestinal Stromal Tumor (GIST) Cecal in Pediatrics? Clinical Case. Mathews J Gastroenterol Hepatol. 7(1):17.

Copyrights: Padrón-Arredondo G, et al. © (2022).

ABSTRACT

Introduction: Gastrointestinal stromal tumors or GISTs are rare and occur mainly in the adult population, but a small percentage (1 to 2%) affect children and adolescents. GISTs are currently considered the most common mesenchymal neoplasm with a potential impact of around 1 to 1.5 cases per 100,000 inhabitants. Clinical Case: A 16-year-old female with no significant history of the case, began her condition with a month of evolution with postprandial fullness, occasional abdominal pain and hematuria. On physical examination it was globose at the expense of an intra-abdominal tumor of 40 x 50 cm of semisolid consistency, the rest of the examination without pathological data. Computed tomography reports “right ovarian tumor” measuring 21 x 22 x 14 cm. Normal laboratory studies. An exploratory laparotomy was performed, locating a tumor dependent on the cecum with implants in the adjacent peritoneum, an ectopic left kidney located in the left iliac fossa. Left hemicolectomy with side-to-side anastomosis is performed. Histopathological report reports spindle cell gastrointestinal stromal tumor with mild low-grade atypia (G1). Inflammatory (myoglandular) polyps with hyperplastic colonic mucosa florid with lymphoid follicles. Discussion: The best way to diagnose GISTs preoperatively is by fine-needle biopsy, although some fear that this system may spread tumors. Up to 85% of pediatric GISTs and 10-15% of adults do not contain the KIT or PDGFRA mutations and are classified as wild-type GISTs that are heterogeneous with respect to their clinical behavior and molecular profile.

Keywords: Gastrointestinal stromal tumors, Cecal, Pediatrics, CT.


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