Cytokine-Based Regenerative Treatment for School Avoidance: A Case Study

¹Ochanomizu Health and Longevity Clinic, Tokyo 101-0062, Japan
²Shirasawa Anti-Aging Medical Institute, Tokyo 101-0062, Japan
³Livant Neurorecovery Center, Guadalajara, Mexico

*Corresponding author: Takuji Shirasawa, Ochanomizu Health and Longevity Clinic, Tokyo 101-0062, Japan, and Shirasawa Anti-Aging Medical Institute, Tokyo 101-0062, Japan, E-mail: [email protected]

Received Date: August 10, 2026
Published Date: August 21, 2026

Citation: Shirasawa T, Cobos LCA. (2026). Cytokine-Based Regenerative Treatment for School Avoidance: A Case Study. Mathews J Case Rep. 11(4):232.

Copyrights: Shirasawa T and Cobos LCA. © (2026).

ABSTRACT

A 16-year-old girl presented to our clinic with school avoidance and reduced social motivation. Comprehensive clinical evaluation, including MRI, EEG, and neurological examination, revealed ADHD-like symptoms associated with paroxysmal EEG activity, spike thrombosis involving the middle cerebral arteries, and MRI findings suggestive of traumatic brain injury. The patient received cytokine-based regenerative treatment targeting epilepsy-related paroxysmal activity, ADHD-like symptoms, and traumatic brain injury. During follow-up, school avoidance improved, social motivation increased, and the patient resumed regular school attendance. To our knowledge, this is the first case report describing improvement in school avoidance following cytokine-based regenerative treatment in association with resolution of EEG abnormalities and MRA findings. These findings may offer a potential therapeutic perspective for school avoidance, which is conventionally managed primarily with cognitive behavioral therapy; however, they should be interpreted cautiously as a temporal association rather than evidence of causality.

Keywords: School Avoidance, Cytokine, Regenerative Medicine, Electroencephalography, Traumatic Brain Injury