Mathews Journal of Case Reports


Previous Issues Volume 6, Issue 2 - 2021

COVID-19 and Sudden Cardiac Death in a Young Man with Myasthenia Gravis

Maysa Ghayyem1, Sara Haseli1, Shekoofeh Yaghmaei2*

1Department of Internal Medicine, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

2University of Fribourg, Fribourg, Switzerland

*Corresponding author: Shekoofeh Yaghmaei, General practitioner, University of Fribourg, Av de Beaumont 5, Lausanne 1012, Fribourg, Switzerland, Tel: +41 78 268 40 50; E-mail: [email protected]

Received Date: June 02, 2021

Publication Date: July 01, 2021

Copyright: Yaghmaei S, et al. © (2021). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation: Maysa Ghayyem, Sara Haseli, Shekoofeh Yaghmaei. (2021). COVID-19 and Sudden Cardiac Death in a Young Man with Myasthenia Gravis. Mathews J Case Rep. 6(2):68.




Myasthenic patients are expected to develop more severe COVID-19 respiratory symptoms compared to the general population because of both respiratory muscle weakness and the possibility of an immunocompromised state related to immunotherapy. During a pandemic like COVID-19, such situation requires meticulous attention, as the entire population is potentially at risk of exposure. However, there is no data on best management for myasthenic patients with COVID infection.

Although pneumonia has been reported as the most common cause of death in COVID-19 patients, sudden cardiac death has also been described in the literature as a possible COVID-19 related mortality cause. Physicians should assess the patient’s cardiac functionas precisely as possible, in addition to the respiratory condition, in order to prevent such incidents. Furthermore, as the cardiac system of myasthenic patients might be negatively influenced by their background, their cardiac system may be even more vulnerable during COVID-19, which should be noted bymedical teams. Reporting such cases can be helpful to develop protocols for treating myasthenic patients during the COVID-19 pandemic.

Here, we present a 37-year-old man with generalized myasthenia gravis who was admitted to our hospital due to dyspnea. He developed severe respiratory distress in few hours and subsequently died of sudden cardiac death.

KEYWORDS: Myasthenia gravis; COVID-19; Sudden cardiac death       

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