Mathews Journal of Cardiology


Previous Issues Volume 7, Issue 2 - 2023

Elevated Troponin: A Comprehensive Review

Mohammad Hassan Kalantar Neyestanaki1, Majid Kalantar2,*

1Department of Medicine, Arak University of Medical Science, Arak, Iran

2Department of Animal Science, Qom Agricultural and Natural Resources Research and Education Center, Qom, Iran

*Corresponding author: Majid Kalantar, Department of Animal Science, Qom Agricultural and Natural Resources Research and Education Center, Qom, Iran, Tel: +982532126495, Email: [email protected].

Received Date: November 17, 2023

Published Date: December 08, 2023

Citation: Neyestanaki MHK, et al. (2023). Elevated Troponin: A Comprehensive Review. Mathews J Cardiol. 7(2):31.

Copyrights: Neyestanaki MHK, et al. © (2023).


Troponin is a complex protein that plays an important role in regulating muscle contraction especially in the heart. It consists of three subunits known as troponin C troponin I and troponin T. When there is damage to a tissue or to the heart troponin is released into the bloodstream making it a valuable biomarker for detecting tissue/cardiac related issues. In recent years, new methods for the early detection of coronary heart diseases have become developed. Acute myocardial infarction (AMI) has been recognized as a clinical condition resulting from atherosclerosis of the coronary arteries. Early diagnosis, facilitated by measurement of elevated troponin levels is a beneficial detection tool to prevent various problems such as coronary heart diseases most notably AMI. Due to high sensitivity of troponin assays, we have notable capabilities to detect minor injuries with greater accuracy. Troponin is a crucial biomarker for diagnosing acute cardiac conditions, yet its elevation in diverse non-cardiac diseases presents a diagnostic challenge. Understanding the significance of recognizing alternative causes of troponin elevation is paramount. It not only prevents misdiagnosis but also ensures accurate identification and timely intervention in cardiac diseases, underscoring the importance of a comprehensive approach to troponin interpretation. This article reviews troponin levels and challenges the conditions that contribute to elevated troponin concentration in the blood. By examining the influencing factors more closely, we gain a deeper understanding of the complex nature of elevated troponin and its diagnostic implications.

Keywords: Acute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS), Kidney Diseases, Pulmonary Disease, Sepsis, Troponin Elevation.

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