Mathews Journal of Veterinary Science


Previous Issues Volume 1, Issue 1 - 2016

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Mathematical Analysis of Antibody Rhythms

Bin Zhao1,2, Lichun Liang1

1College of Science, Northwest A&F University, Yangling, Shaanxi, China.

2School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China.

Corresponding Author: Bin Zhao, College of Science, Northwest Agriculture and Forestry University, Yangling, 712100, China, 
Tel: +86 130 28517572; Email[email protected]

Received Date: 30 Jul 2016 
Accepted Date: 22 Aug 2016 
Published Date: 01 Sep 2016

Copyright © 2016 Zhao B

Citation: Zhao B and Liang L. (2016). Mathematical Analysis of Antibody Rhythms. Mathews J Vet Sci. 1(1): 004.



The aim of this study is to develop biomathematical models with important physiological parameters involving immune response for antibody rhythms by using the circadian, infradian and ultradian rhythms of IgY antibody, which could be used in many aspects, for instance to explain the controversies concerning antibody concentration with biological reasons and biomathematical calculations, to optimize the antibody yield in large scale production. In general, this approach could be extended to construct computational models for other antibodies using their biological rhythms to describe their physiological and pathophysiological mechanisms. This approach would aid to utilize the engineered antibodies and their derivatives for various biomedical applications.


Antibody Rhythm; Immune Clock; Chronobiology; Biomathematical Model.

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