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Previous Issues Volume 2, Issue 1 - 2018
The Prevalence of Vitamin D Deficiency in Patients with Hashimoto's Hypothyroidism
Mahdis Solhjoo1*, Alireza Rastgoo Haghi2, Nasim Golchin3, Zahra Ahmadvand4, Hossein Moin Tavakoli4
1Department of Medicine, Nassau University Medical Center, USA, NY.
2Department of Pathology, Hamadan University of Medical Sciences, Hamadan, Iran.
3Department of Medicine, Icahn School of Medicine at Mount Sinai Queens Hospital Center, NY, USA.
4Department of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Corresponding Author: Mahdis Solhjoo, Department of Medicine, Nassau University Medical Center, USA, NY.
Tel: 15165720123; E-Mail: [email protected]
Received Date: 27 Jul 2018
Accepted Date: 07 Aug 2018
Published Date: 13 Aug 2018
Copyright © 2018 Solhjoo M
Citation: Solhjoo M, A Rastgoo Haghi, Ahmadvand Z, Golchin N, et al. (2018). The Prevalence of Vitamin D Deficiency in Patients with Hashimoto's Hypothyroidism. M J Immu. 2(1): 006.
ABSTRACT
Introduction:Vitamin D has some anti-inflammatory and immune-modulating attributes and in recent studies its low levels has been associated with some autoimmune diseases. Hashimoto's hypothyroidism is one of the most common endocrine disease worldwide and in this study the aim is to investigate the relation between the level of vitamin D and Hashimoto's hypothyroidism.
Material and Methodes:40 patients with hypothyroidism and 40 healthy subjects with normal TSH level were selected from Besat Hospital, Hamadan, Iran during the period of April to August 2016. Their serum levels of 25 (OH) D, Anti-TPO and TSH were checked and recorded in the checklist.
Results:There was a significant difference between the two groups in terms of vitamin D mean. Also the vitamin D mean in patients with subclinical and clinical Hashimoto's disease was 18.3 ng/ml and 5.52 ng/ml respectively and the difference was statistically significant. Based on logistic regression test there was no significant difference between serum levels of vitamin D and TSH in both groups.
Conclusion: Based on the results it can be concluded that there is an association between low level of vitamin D and Hashimoto's thyroiditis.
KEYWORDS
Vitamin D; Hypothyroidism; Hashimoto's; Autoimmune Disease.
