Formulation and Evaluation of Organogels of Actives from Piper Betel for Treatment of Cellulitis

JSPM’s Jayawantrao Sawant College of Pharmacy and Research, Hadapsar, Pune-411028, India

*Corresponding author: Prashant Suryawanshi, JSPM’s Jayawantrao Sawant College of Pharmacy and Research, Hadapsar, Pune-411028, India, Phone: 7559390868, E-mail: [email protected]

Received Date: July 13, 2025

Published Date: September 30, 2025

Citation: Prashant S, et al. (2025). Formulation and Evaluation of Organogels of Actives from Piper Betel for Treatment of Cellulitis. Mathews J Pharma Sci. 9(3):55.

Copyrights: Prashant S, et al. © (2025).

ABSTRACT

Topical drug delivery system of organogel of actives form of P Betel leaf oil is used to treat bacterial infection of cellulitis disease. The deeper layers of the skin and underlying tissues are affected by the common bacterial skin illness known as cellulitis. This study describes the organogel by using gelling agent soya lecithin and polymer Poloxamer 407 to obtain the drug released and drug content. Physicochemical characterization was performed for evaluation of the betel leaf oil on TLC, HPTLC and anti-oxidant activity. The formulation of organogel was evaluated for an organoleptic observation, measurement of pH, viscosity, spediability, in-vitro drug released, anti-bacterial activity, skin irritation test and stability test. Through this study, increase the drug released of organogel as increasing the concentration of gelling agent. Concentration of soya lecithin (2.5%) is then the drug released show the minimum released. Hence, gelling agent and polymer is responsible for the variation of % of drug released.

Keywords: Anti-Bacterial Activity, Antioxidant Activity, Skin Irritation Activity, Drug Released, Drug Content.