Chemistry, Origin, Antitumor and Other Activities of Fungal Homo-Dimeric Alkaloids

¹Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
²Institute for Drug Discovery, P.O. Box 45289, Jerusalem 91451, Israel.
Corresponding Author:Valery M Dembitsky, Institute for Drug Discovery, 8 Ha-Marpe Str, P.O. Box 45289, Jerusalem 91451, Israel, Tel: +972-526877444; E-Mail: [email protected]
Received Date: 27 Feb 2016  
Accepted Date: 17 Mar 2016  
Published Date: 23 Mar 2016
​Copyright © 2016 Dembitsky VM
Citation: Kuklev DV and Dembitsky VM. (2016). Chemistry, Origin, Antitumor and Other Activities of Fungal Homo-Dimeric Alkaloids.Mathews J Pharm Sci. 1(1): 004.

ABSTRACT:

Homo-dimeric alkaloids produced by fungi, lichenized fungi and fungal endophytes are a structurally unique class of natural products with extensive biological activities that are presented in this article. More than 100 selected fungal metabolites have been confirmed to exhibit antitumor, antimicrobial, antibacterial, and other activities

KEYWORDS:
Homo-dimeric; Alkaloids; Fungi; Fungal Endophytes; Lichens Activities.