Mathews Journal of Pharmaceutical Science

2474-753X

Previous Issues Volume 2, Issue 1 - 2017

Research Article PDF  

Antimicrobial Efficacy of Callus and in Vitro Leaf Extracts of Sapindus Mukorossi Gaertn. Against Pathogenic Microbes

Reetika Singh1,2 , Nishi Kumari1 , Gopal Nath3

1Department of Botany, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India.

2Centre of Advance Study in Botany, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India.

3Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India

Corresponding Author: Nishi Kumari, Department of Botany, MMV Banaras Hindu University, Varanasi-221005, UP, India, 
Tel: 91-9450790415; E-Mail: kumaridrnishi@yahoo.co.in

Received Date: 29 Oct 2016  
Accepted Date: 28 Nov 2016  
Published Date: 01 Dec 2016

Copyright © 2016 Kumari N

Citation: Reetika S, Kumari N and Nath G. (2016). Antimicrobial Efficacy of Callus and in Vitro Leaf Extracts of Sapindus Mukorossi Gaertn. Against Pathogenic Microbes. Mathews J Pharm Sci. 2(1): 009.

 

ABSTRACT:

Sapindus mukorossi is well known medicinal and economical plant. Antibacterial and antifungal activities were evaluated from various extracts (ethanolic, methanolic and aqueous) of callus and in vitro leaf against several Gram positive and Gram negative bacteria and clinically isolated fungus. Antimicrobial activities were more in in vitro leaf extracts. Callus extract have showed antibacterial activity against S. aureus and E. coli. Maximum inhibition zone (8.06 ± 0.17 mm) was observed against C. tropicalis from methanolic extracts of in vitro leaf. In vitro leaf extracts have shown efficient antifungal activity. Callus and in vitro leaf extract can be used for production of different phytochemicals and plant based antibiotics.

KEYWORDS:

Antimicrobial; Medicinal Plant; Sapindus Mukorossi; Plant Extract.


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