Ezegbe Chekwube Andrew1,3,*, Okorafor Ezinne Chinemerem2, Ogbonna Emmanuel Emeka4, Ezegbe Amarachi Grace5, Olenyi Ogbonna Christantus1
1Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria
2Department of Pharmacology, School of Basic Clinical Sciences, Federal University of Technology, Owerri, Imo State, Nigeria
3Nanoscience and Advanced Materials, Graduate Program (PPG-Nano), Federal University of ABC, Avenida dos Estados, 5001, 09210-580, Santo Andre, Sao Paulo, Brazil
4Department of Pharmaceutical Microbiology, University of Port-Harcourt, Nigeria
5Department of Home Science and Management, University of Nigeria, Nsukka, Nigeria
*Corresponding author: Ezegbe Chekwube Andrew, Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria & Nanoscience and Advanced Materials, Graduate Program (PPG-Nano), Federal University of ABC, Avenida dos Estados, 5001, 09210-580, Santo Andre, Sao Paulo, Brazil, Tel: +2348038042802, E-mails: [email protected]; [email protected]
Received Date: June 09, 2025
Published Date: July 08, 2025
Citation: Andrew EC, et al. (2025). A Review on Recent Advances Using Green Nanotechnological Approaches in the Treatment of Malaria. Mathews J Pharma Sci. 9(3):53.
Copyrights: Andrew EC, et al. © (2025).
ABSTRACT
Malaria is a tropical disease that affects more than 2.7 million people annually. There are various species of plasmodium associated with malaria. They include Plasmodium falciparium, P. vivax, P. malariae and P. Ovale. Major challenges associated with malaria infection are resistance to antimalarial drugs and the lack of an effective vaccine against malaria. There are new prospects that have evolved in the treatment of malaria which include recent developments in nanotechnology. This is due to the fact that these nanoparticles possess unique characteristics such as less toxicity, high biocompatibility, environmentally friendly and cost effective. The use of plants and micro-organisms in the development of green nanoparticles have been documented. This review was carried out to ascertain the recent advances in the use of nanotechnological approach in the treatment of malaria. Prevalence of malaria is due to widespread drug resistance to antimalarial drugs and insecticides used to control vectors. These limitations have led to the development of new approaches to combat this tropical disease.
Keywords: Malaria, Antimalarial drugs, Nanotechnology, Nanoparticles.