Mathews Journal of Neurology

2572-6536

Previous Issues Volume 2, Issue 1 - 2017

Research Article Full-Text  PDF  

Burden of Atrial Fibrillation in Patients with Spontaneous Intracerebral Hemorrhage in Florence District over the Years

Luca Masot1, 2*, Federico Moroni1, Vieri Vannucchi1, Elisa Grifoni2, Giancarlo Landini1, Filippo Cellai3, Stefano Spolveri4, Mauro Pratesi5, Anna Poggesi6, Domenico Inzitari6

1Department of Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy.

2Department of Internal Medicine, San Giuseppe Hospital, Empoli, Italy.

3Department of Informatic and Health Technologies, ESTAR, Tuscany, Italy.

4Department of Internal Medicine, Borgo San Lorenzo Hospital, Florence, Italy.

5Department of Emergency, Santa Maria Nuova Hospital, Florence, Italy.

6Neuroscience Section, Department of Neurofarba, University of Florence, Florence, Italy.

Corresponding Author: Luca Masotti, Internal Medicine, Santa Maria Nuova Hospital, Piazza Santa Maria Nuova 1, 50122 Florence, Italy, Tel: 00855-16-241-666; E-Mail:  [email protected]

Received Date: 22 Mar 2017
Accepted Date: 22 May 2017
Published Date: 26 May 2017
Copyright © 2017 Masotti L
Citation: Bhalla D and Lotfalinezhad E. (2016). A Short Perspective on the Risk Profile of Epilepsy in Iran. Mathews J Neurol. 1(1): 003.

 

ABSTRACT

Background and aim: Literature evidence about the burden of atrial fibrillation (AF) in patients with spontaneous intracerebral hemorrhage (ICH) is lacking. Therefore, the aim of our study was to answer this issue.

 

Materials and methods: We reviewed the International Classification of Diseases, 9th revision, Clinical Modification (ICD- 9th CM) database referred to patients discharged from the six Hospitals of Florence district, Italy, in a 15-year period (2001- 2015). Code 431 (spontaneous ICH) was searched as primary or secondary diagnosis, and then matched with code 427.31 (AF) in one of the other discharge diagnoses.

 

Results: Overall, 7452 patients were discharged with ICH as primary or secondary diagnosis. Of them, 693 (9.2%) had AF. The burden of AF increased with age (1.5% in patients under the age of 65 years, 6.4% in patients aged 65-75 years, and 12.8% in those older than 75 years), and over the years (5.6% in 2001, 8.9% in 2008, and 11.4% in 2015), irrespective of age. In-hospital mortality decreased over the years both in patients with and without AF. However, in-hospital mortality in patients with AF-related ICH was significantly higher than in patients without AF (29.4% vs 23.3%, p=0.04).

 

Conclusion: Our study demonstrates that, in patients with spontaneous ICH, the burden of AF is absolutely not negligible, and seems to be increasing over the years.

 

KEYWORDS

Intracerebral Hemorrhage; Atrial Fibrillation; Burden; Mortality.


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