Mathews Journal of Immunology & Allergy


Current Issue Volume 7, Issue 1 - 2023

Role of Autoimmunity in Development of Type 2 Diabetes

Yongxin Zhang*

Zyxell Inc. Carrollton, Texas, USA

*Corresponding author: Yongxin Zhang, Zyxell Inc. Carrollton, Texas 75007, USA, Tel: 9723518317, 9729758600; Fax: 9728207820; Email: [email protected].

Received Date: November 29, 2022

Published Date: January 12, 2023

Citation: Zhang Y. (2023). Role of Autoimmunity in Development of Type 2 Diabetes. Mathews J Immunol Allergy. 7(1):17.

Copyrights: Zhang Y. © (2023).


The mechanisms that underlie Type 2 diabetes are complex and far less illustrated compared to Type 1 diabetes which has been acknowledged as an autoimmune disease. It has been hypothesized that autoimmunity, autophagy, or/and dedifferentiation of islet β cells and other factors could be involved in the development of Type 2 diabetes, in which autoimmunity may also play a critical role.

Keywords: Diabetes, Autoimmunity, Immune Cells, Insulin, Islet Β Cells, Autophagy, Dedifferentiation, Insulin Resistance, Hyperglycemia.

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