¹Specialist of Internal Medicine, MD, Turkey

²Manager of Writing and Statistics, Turkey

³Ministry of Health of Turkey, MD, Turkey

⁴Middle-East Academy for Medicine of Aging, MD, Lebanon

⁵Medi-WORLD International, Australia

*Corresponding author: Prof Dr. Mehmet Rami Helvaci, MD, Specialist of Internal Medicine, 07400, ALANYA, Turkey, Phone: 00-90-506-4708759; Email: [email protected].

Received Date: March 30, 2023

Published Date: April 15, 2023

Citation: Helvaci MR, et al. (2023). What A Low Prevalence of Diabetes Mellitus in Digital Clubbing. Mathews J Diabetes Obes. 6(1):15.

Copyrights: Helvaci MR, et al. © (2023).

ABSTRACT

Background: There may be some significant relationships between digital clubbing, fasting plasma glucose (FPG), and diabetes mellitus (DM). Method: All cases with digital clubbing were included. Results: The study included 104 patients (85 males) with digital clubbing detected among 2.428 cases (1.044 males), in total. So clubbing was higher in males, significantly (8.1% versus 1.3%, p<0.001). The mean age of clubbing cases was 49.2 years, and there was a male predominance (81.7%), again. Parallel to the male predominance, there were higher prevalences of smoking (69.2% versus 41.6%, p<0.001) and chronic obstructive pulmonary disease (COPD) (27.8% versus 10.8%, p<0.001) in the clubbing cases. Although the mean body weight, body mass index (BMI), and FPG were lower in the clubbing cases, the differences were nonsignificant probably due to the small sample size of the study. Similarly, DM was lower in the clubbing cases, significantly (12.5% versus 21.6%, p<0.05). The systolic blood pressure (BP) was also lower in the clubbing cases, significantly (127.6 versus 136.9 mmHg, p= 0.011). On the other hand, coronary heart disease (CHD) and/or peripheric artery disease (PAD) were higher in the digital clubbing cases, significantly (7.6% versus 0.0%, p<0.01). Conclusion: There are some significant relationships between digital clubbing, smoking, COPD, CHD, and PAD probably due to the strong atherosclerotic effects of smoking. Similarly, the mean body weight, BMI, FPG, systolic BP, and DM are inversely related to digital clubbing probably due to the severe inflammatory effects of smoking on the vascular endothelium all over the body, again.

Keywords: Digital Clubbing, Smoking, Fasting Plasma Glucose, Diabetes Mellitus, Triglycerides, Acute Phase Reactants, Atherosclerosis.